Mit dem Pilzgift Canditoxin dezimiert der 'harmlose'
Candida albicans-Pilz die guten Bakterien der Darmflora und schädigt genau
jene IgA-Antikörper, die an der Reparatur der Darmschleimhaut beteiligt
sind. Mit Hilfe der Hyphen kann der Pilz dann tief in das Gewebe eindringen.
Dies ist der
Wirkmechanismus bei Krankheiten wie Morbus Crohn und dergl..
Morbus Crohn 2024:
recent studies
have shifted towards host genetics and host-fungal interactions. The
mycobiota is a vital component of the gastrointestinal microbial community
and plays a significant role in immune regulation. Among fungi,
Candida
species, particularly
Candida albicans
(C. albicans),
have been extensively studied due to their dual role as gut commensals and
invasive pathogens. Recent findings indicate that various strains of
C. albicans
exhibit considerable differences in
virulence factors, impacting IBD's pathophysiology. Intestinal fungal
dysbiosis and antifungal mucosal immunity may be associated to IBD,
especially Crohn's disease (CD)

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